Mitochondria 101

Your body is constantly fighting to stay healthy. 

All it needs is the right support.

Salugenesis

Salutogenesis (coined by medical sociologist Aaron Antonovsky in his book, Health, Stress and Coping) is an approach that focuses on the origins of health versus the origins of disease. This approach considers the body’s potential to sustain health and well-being is central to living a healthful life.

Taking this concept further, Robert K. Naviaux, MD, PhD, professor of Medicine, Pediatrics and Pathology at UC San Diego School of Medicine, defines a more narrow focus – Salugenesis – on the molecular, metabolic, and cellular stages of the healing cycle. It is the process by which the body tries to heal itself in response to physical and mental stresses. In Salugenesis, every molecule, every cell and every organ inside the body takes part in this self-healing process. Together, they fight to keep your body in optimal health.

What provides the power for this fight?
Mitochondria. (More about them later)

The science behind all of this? Not so simple.

Salugenesis

Bioenergetics

Mitochondria

Mitochondrial biogenesis

Mitophagy

Mitokatlyst

Bioenergetics

Simply put, bioenergetics can be described as the flow of energy through all living things. There are three key bioenergetic processes: cellular respiration in animals, photosynthesis in plants, and metabolism. The cell transforms energy by producing, storing, or using adenosine triphosphate (ATP) which can be understood as the main energy currency used to fuel health and well-being, growth, vitality, physical activities, and mental clarity.

Metabolism is the set of chemical reactions that a) convert the energy in food into energy ton fuel processes in cells, b) convert food into molecules that are the building blocks of proteins, lipids, nucleic acids and carbohydrates, and c) eliminate waste products.

Mitochondria

Mitochondria, the powerhouses of your cell, are subcellular structures with a specific job description: generate chemical energy to power the cell’s biochemical reactions. Except for red blood cells, every cell in your body can contain thousands of mitochondria.

Mitochondria utilize the energy released during the oxidation of the food you eat to generate adenosine triphosphate (ATP). ATP, also known as the ‘energy currency of the cell,’ is the human body’s primary energy source.

Some of the critical body functions powered by mitochondria

Strength and endurance of heart and skeletal muscles
Blood flow to the heart and muscle
Maintaining healthy blood sugar levels
Renal filtration and transport functions

0 %

of your energy
is generated by your mitochondria

of each heart muscle cell is made up of mitochondria

of each liver cell is made up of mitochondria

Mitochondrial biogenesis

Mitochondrial biogenesis is the process by which cells create new mitochondria. It starts with the cell nucleus releasing hormones that trigger mitochondrial division and growth. The more mitochondria there are in your body, the more energy for your body to use. Which means walking more, running faster, recovering from exhaustion quicker, and generally feeling full of life.

The interesting thing about mitochondrial biogenesis is that we can influence it through our lifestyle choices. For instance, studies have shown that repeated bouts of endurance exercise stimulate mitochondrial biogenesis in skeletal muscles.

Mitophagy

Mitophagy, a cellular process, is your body’s way of dealing with damaged mitochondria. It breaks them down, recycles their components, or removes them entirely.

During their lifecycle, mitochondria constantly divide (fission) and bond (fusion) to meet your body’s energy demands.

Fission allows the cell to segregate and degrade dysfunctional mitochondria through mitophagy. The healthy mitochondrion from each division continues the cycle of fission and fusion till it wears out. After a person turns 20, they lose approximately 10% of their mitochondrial density every decade. Aging, illnesses and mental stress also damage the mitochondria and cause them to dysfunction.

Mitokatlyst

In 2004, our scientists made the groundbreaking discovery that the hormone 11-𝛃-hyroxy-pregnenolomne and its oxidized metabolite 11-𝛃-hyroxy=progesterone may hold the key to mitochondrial biogenesis.

This hormone and its oxidized metabolite bind to the Estrogen-Related Receptors (ERR) and signal the cell nucleus to activate mitochondrial biogenesis, protect the mitochondria, and create more energy by burning fat instead of glucose.

Mitokatlyst is the result of 20 years of peer-reviewed scientific research and experiments. It has been thoroughly tested and proven safe for consumption, with multiple clinical studies on both animals and humans to support its efficacy. The studies also show that Mitokatlyst is readily absorbed and biologically active even at nanomolar doses.