Science based.
Heart led.
Camellia Sinensis standardized to 98% pure (-)- Epicatechin, the key ingredient in our product, is known to stimulate mitochondrial biogenesis, support ATP production, protect mitochondria from damage and dysfunction, and support optimal mitophagy.*
Structural requirements for (-)Epicatechin activity are highly specific. Closely related structural analogs not only have no efficacy but can also antagonize the effect of this molecule. The product has an exceptional Safety Profile and works at a precise dose and purity.
Supporting literature
- Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (−)-epicatechin in healthy volunteers.*(−)-Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy.*
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Acute effects of an oral supplement of (-)-epicatechin on postprandial fat and carbohydrate metabolism in normal and overweight subjects.*
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A randomized, placebo-controlled, double-blind study on the effects of (−)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects.*
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Other Select Research
(−)-Epicatechin Activation of Endothelial Cell Endothelial Nitric Oxide Synthase, Nitric Oxide, and Related Signaling Pathways*
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- 11-β-hydroxysterols as possible endogenous stimulators of mitochondrial biogenesis as inferred from epicatechin molecular mimicry*
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New Clinical Trials
Chronic Kidney Disease (CKD)
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Human clinical trial to evaluate the effect of (-)-Epicatechin (Blue Oak Nutraceuticals inc. Mitokatlyst™ – E) on mitochondrial dysfunction, muscle function, muscle mass, and myosteatosis in Chronic Kidney Disease (CKD). Initiated at Karolinska Institutet, Sweden. ClinicalTrials.gov ID – NCT06631820
* Studies conducted in the U.S. under the guidelines issues by the US FDA.