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(−)-Epicatechin dosing in normal and overweight test subjects showed an increase in fat burning and lowering of blood glucose and triglycerides after consuming a meal

Published March 2014
Twenty adult volunteers (normal and overweight) participated in this crossover, open-labeled study. The test criteria excluded those with chronic diseases or those who used pharmacologic agents to modulate metabolism after a meal. Some of the test subjects received a dose of 100 mg of a precise purity of (-)-epicatechin (key ingredient in Mitokatylst™ – E) after fasting for 10 hours and before consuming a balanced commercial nutritional supplement. All test subjects were tested for their blood glucose and triglyceride levels before, 2 hours after, and 4 hours after consuming the nutritional supplement.

Key Takeaways

  • The treated group showed a significant increase in fat burning after the meal; in addition, the overweight subjects demonstrated a larger increase in fat burning.
  • Test results for the normal subjects in the treated group showed significantly lower glucose (four hours after the meal) and triglycerides (immediately after consuming the meal); the overweight subjects showed significant decreases in fasting glycemia and post-eating triglyceridemia.
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Authors Gabriela Gutiérrez-Salmeán, Pilar Ortiz-Vilchis, Claudia M Vacaseydel, Ivan Rubio-Gayosso, Eduardo Meaney, Francisco Villarreal, Israel Ramírez-Sánchez, Guillermo Ceballos