(−)-Epicatechin dosing in normal and overweight test subjects showed an increase in fat burning and lowering of blood glucose and triglycerides after consuming a meal
Published March 2014
Twenty adult volunteers (normal and overweight) participated in this crossover, open-labeled study. The test criteria excluded those with chronic diseases or those who used pharmacologic agents to modulate metabolism after a meal. Some of the test subjects received a dose of 100 mg of a precise purity of (-)-epicatechin (key ingredient in Mitokatylst™ – E) after fasting for 10 hours and before consuming a balanced commercial nutritional supplement. All test subjects were tested for their blood glucose and triglyceride levels before, 2 hours after, and 4 hours after consuming the nutritional supplement.
Key Takeaways
The treated group showed a significant increase in fat burning after the meal; in addition, the overweight subjects demonstrated a larger increase in fat burning.
Test results for the normal subjects in the treated group showed significantly lower glucose (four hours after the meal) and triglycerides (immediately after consuming the meal); the overweight subjects showed significant decreases in fasting glycemia and post-eating triglyceridemia.
Authors
Gabriela Gutiérrez-Salmeán, Pilar Ortiz-Vilchis, Claudia M Vacaseydel, Ivan Rubio-Gayosso, Eduardo Meaney, Francisco Villarreal, Israel Ramírez-Sánchez, Guillermo Ceballos